They asked for a screenshot of the library paths in ST4. I contacted IK Multimedia support last night, and they got back to me today via email. However, I got a weird solution that seems to have fixed the issue. Thanks for the replies and suggestions, folks. But if I click the upper right hand 'X' and close the GUI window, every DAW crashes without fail.

It does NOT happen if I minimize the GUI or just remove the instrument without closing the GUI. Update: I initially said this happens when I close the GUI or remove the instrument, but actually it happens when the GUI window is closed. I've already deleted the ST4 app and reinstalled it at least twice, and I went through the mind-numbing task of re-installing the libraries, too. I'm running the most recent install of SampleTank 4, the most recent update of Cakewalk (and Cubase 12, Cubase 11 and the other DAWs also), on Windows 10 Pro 64 bit. So far, I can make it happen without fail, every time. Does the same to Cubase 12 (and 11), Studio One 5 Artist and Reaper 6. Has anyone started experiencing problems with ST4 crashing their DAWs? I have been having issues the last day or so: ST4 loads just fine, runs instruments just fine, but if I close the GUI, it crashes Cakewalk immediately.

Sampletank